CXCR6 Recombinant Rabbit Monoclonal Antibody [JE66-40]
C-X-C chemokine receptor type 6 is a protein that in humans is encoded by the CXCR6 gene. CXCR6 has also recently been designated CD186 (cluster of differentiation 186). CXCR6 has been identified as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. It is a minor coreceptor for HIV-1, nearly all strains of which use CCR5 and/or CXCR4. Most SIV strains can use CXCR6 and recent evidence suggests that in monkeys that serve as the natural hosts of SIV, CXCR6 may be a major coreceptor. CXCR6 was previously known as "Bonzo" and "STRL33" in the HIV/SIV field.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CXCR6, BONZO, STRL33, TYMSTR
Swiss Prot
O00574 Human
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human CXCR6 aa 1-100.
Isotype
IgG
Clone
JE66-40
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
JAR cell lysate, SW480 cell lysate, human placenta tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 39 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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