Flopropione

Flopropione is a 5-HT receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor[1][2]. Flopropione also as an antispasmodic agent[3].

Product Specifications

CAS Number

[2295-58-1]

UNSPSC

12352005

Hazard Statement

H301

Target

5-HT Receptor; COMT

Type

Natural Products

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Flopropione.html

Concentration

10mM

Purity

99.97

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CCC(C1=C(O)C=C(O)C=C1O)=O

Molecular Formula

C9H10O4

Molecular Weight

182.17

Precautions

H301

References & Citations

[1]Burns SM, et al. High-throughput luminescent reporter of insulin secretion for discovering regulators of pancreatic Beta-cell function. Cell Metab. 2015 Jan 6;21 (1) :126-37.|[2]C Barlow, et al. Modulation of neurogenesis using d-cycloserine combinations. 2010-08-26. PAT - US2010216805.|[3]Ohgaki K, et al. Facilitation of expulsion of ureteral stones by addition of α1-blockers to conservative therapy. Scand J Urol Nephrol. 2010 Dec;44 (6) :420-4.