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Lumefantrine

Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug with oral activity[1][2].

Product Specifications

CAS Number

82186-77-4

Product Name Alternative

Benflumetol

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Lumefantrine.html

Purity

99.40

Solubility

DMF : 25 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 2 mg/mL (ultrasonic)

Smiles

OC(CN(CCCC)CCCC)C1=CC(Cl)=CC(/C2=C\C3=CC=C(Cl)C=C3)=C1C4=C2C=C(Cl)C=C4

Molecular Formula

C30H32Cl3NO

Molecular Weight

528.94

Precautions

H302, H315, H319, H335

References & Citations

[1]Ndounga M, et al. Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study. Malar J. 2015 Oct 29;14 (1) :423.|[2]Yufan Ma, et al. Enhanced antimalarial activity by a novel artemether-lumefantrine lipid emulsion for parenteral administration. Antimicrob Agents Chemother. 2014 Oct;58 (10) :5658-65.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

Plasmodium

Available Sizes

Frequently Asked Questions

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