Lumefantrine
Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug with oral activity[1][2].
Product Specifications
CAS Number
82186-77-4
Product Name Alternative
Benflumetol
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Lumefantrine.html
Purity
99.40
Solubility
DMF : 25 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 2 mg/mL (ultrasonic)
Smiles
OC(CN(CCCC)CCCC)C1=CC(Cl)=CC(/C2=C\C3=CC=C(Cl)C=C3)=C1C4=C2C=C(Cl)C=C4
Molecular Formula
C30H32Cl3NO
Molecular Weight
528.94
Precautions
H302, H315, H319, H335
References & Citations
[1]Ndounga M, et al. Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study. Malar J. 2015 Oct 29;14 (1) :423.|[2]Yufan Ma, et al. Enhanced antimalarial activity by a novel artemether-lumefantrine lipid emulsion for parenteral administration. Antimicrob Agents Chemother. 2014 Oct;58 (10) :5658-65.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Plasmodium
Available Sizes
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