Maleimide-NOTA
Maleimide-NOTA is a chelator for the labeling of peptides and antibodies. Maleimide-NOTA can react with cysteine[1].
Product Specifications
CAS Number
[1295584-83-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Radionuclide-Drug Conjugates (RDCs)
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/maleimide-nota.html
Purity
99.69
Solubility
H2O : 175 mg/mL (ultrasonic)
Smiles
O=C(O)CN1CCN(CC(NCCN2C(C=CC2=O)=O)=O)CCN(CC(O)=O)CC1
Molecular Formula
C18H27N5O7
Molecular Weight
425.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Dora Mugoli Chigoho, et al. Site-Specific Radiolabeling of a Human PD-L1 Nanobody via Maleimide-Cysteine Chemistry. Pharmaceuticals (Basel) . 2021 Jun 8;14 (6) :550.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RDC Bifunctional Chelator
Available Sizes
Curated Selection
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