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JQKD82 (trihydrochloride)

JQKD82 (JADA82) trihydrochloride is a cell-permeable and selective KDM5 inhibitor. JQKD82 trihydrochloride increases H3K4me3 and can be used for the research of multiple myeloma[1].

Product Specifications

CAS Number

[2863676-87-1]

Product Name Alternative

JADA82 (trihydrochloride) ; PCK82 (trihydrochloride)

UNSPSC

12352005

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/jqkd82-trihydrochloride.html

Purity

99.89

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(CNCC(N(CCN(C)C)CC)=O)=NC=C1)OC2=CC=C(C=C2OC(C)C)OC(C)C.[H]Cl.[H]Cl.[H]Cl

Molecular Formula

C27H43Cl3N4O5

Molecular Weight

610.01

References & Citations

[1]Jun Qi, et al. Histone demethylase 5 inhibitors and uses thereof. WO2020033377A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

KDM5

Available Sizes

Curated Selection

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