CC-90001
Product Specifications
UNSPSC Description
CC-90001 is a potent, selective and orally active inhibitor of c-Jun N-terminal kinase (JNK). CC-90001 shows 12.9-fold selectivity for JNK1 over JNK2 in a cell-based model. CC-90001 can be used for the research of idiopathic pulmonary fibrosis[1][2].
Target Antigen
JNK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cc-90001.html
Smiles
O=C(C1=CN=C(NC(C)(C)C)N=C1N[C@H]2C[C@@H](O)[C@H](C)CC2)N
Molecular Weight
321.42
References & Citations
[1]Bennett B, et, al. CC-90001, a Second Generation Jun N-Terminal Kinase (JNK) Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine 2017; 195:A5409.|[2]Kolb M, et, al. Therapeutic targets in idiopathic pulmonary fibrosis. Respir Med. 2017 Oct;131:49-57.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-138304/CC-90001-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-138304/CC-90001-SDS-MedChemExpress.pdf
CAS Number
1403859-14-2
Available Sizes
Curated Selection
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