3′-O-Methylcytidine

3′-O-Methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

Product Specifications

CAS Number

[20594-00-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3-o-methylcytidine.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O[C@@H]1[C@H](OC)[C@@H](CO)O[C@H]1N2C=CC(N)=NC2=O

Molecular Formula

C10H15N3O5

Molecular Weight

257.24

Precautions

H302, H315, H319

References & Citations

[1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3 (11) :1062-8.