CAY10781

CAY10781 (Compound 11) is an inhibitor of the neuropilin-1 (NRP-1) and VEGF-A interaction. CAY10781 inhibits VEGF-A-induced phosphorylation of VEGFR2 in Catecholamine A-differentiated (CAD) cells[1].

Product Specifications

CAS Number

[1210360-87-4]

UNSPSC

12352005

Target

VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cay10781.html

Smiles

O=C(O)CC1=CN=C(C2=CC=CN=C2)NC1=O

Molecular Formula

C11H9N3O3

Molecular Weight

231.21

References & Citations

[1]Perez-Miller S, et al. In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike protein. bioRxiv [Preprint]. 2020 Sep 23:2020.09.22.308783.