CAY10781
CAY10781 (Compound 11) is an inhibitor of the neuropilin-1 (NRP-1) and VEGF-A interaction. CAY10781 inhibits VEGF-A-induced phosphorylation of VEGFR2 in Catecholamine A-differentiated (CAD) cells[1].
Product Specifications
CAS Number
1210360-87-4
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cay10781.html
Smiles
O=C(O)CC1=CN=C(C2=CC=CN=C2)NC1=O
Molecular Formula
C11H9N3O3
Molecular Weight
231.21
References & Citations
[1]Perez-Miller S, et al. In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike protein. bioRxiv [Preprint]. 2020 Sep 23:2020.09.22.308783.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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