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Hydrocortisone cypionate

Product Specifications

UNSPSC Description

Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.

Target Antigen

Glucocorticoid Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation;Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Hydrocortisone_cypionate.html

Purity

98.04

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

C[C@@]1([C@@]2(O)C(COC(CCC3CCCC3)=O)=O)[C@](CC2)([H])[C@@](CCC4=CC5=O)([H])[C@]([C@]4(CC5)C)([H])[C@@H](O)C1

Molecular Weight

486.64

References & Citations

[1]F?rster C, et al. Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier. J Physiol. 2008 Apr 1;586(7):1937-49.|[2]Bellinghausen I, et al. Inhibition of human allergic T-cell responses by IL-10-treated dendritic cells: differences from hydrocortisone-treated dendritic cells. J Allergy Clin Immunol. 2001 Aug;108(2):242-9.|[3]Chappell D, et al. Hydrocortisone preserves the vascular barrier by protecting the endothelial glycocalyx. Anesthesiology. 2007 Nov;107(5):776-84.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-U00089/Hydrocortisone-cypionate-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-U00089/Hydrocortisone-cypionate-SDS-MedChemExpress.pdf

Clinical Information

Launched

CAS Number

508-99-6

Available Sizes

Curated Selection

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