Hydrocortisone cypionate
Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.
Product Specifications
CAS Number
508-99-6
UNSPSC
12352211
Hazard Statement
H315-H319-H320
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Hydrocortisone_cypionate.html
Concentration
10mM
Purity
98.04
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
C[C@@]1([C@@]2(O)C(COC(CCC3CCCC3)=O)=O)[C@](CC2)([H])[C@@](CCC4=CC5=O)([H])[C@]([C@]4(CC5)C)([H])[C@@H](O)C1
Molecular Formula
C29H42O6
Molecular Weight
486.64
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]F?rster C, et al. Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier. J Physiol. 2008 Apr 1;586 (7) :1937-49.|[2]Bellinghausen I, et al. Inhibition of human allergic T-cell responses by IL-10-treated dendritic cells: differences from hydrocortisone-treated dendritic cells. J Allergy Clin Immunol. 2001 Aug;108 (2) :242-9.|[3]Chappell D, et al. Hydrocortisone preserves the vascular barrier by protecting the endothelial glycocalyx. Anesthesiology. 2007 Nov;107 (5) :776-84.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
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Available Sizes
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