Val-Cit
Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[159858-33-0]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/val-cit.html
Purity
99.76
Solubility
H2O : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)[C@H](CCCNC(N)=O)NC([C@H](C(C)C)N)=O
Molecular Formula
C11H22N4O4
Molecular Weight
274.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140014/Val-Cit-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140014/Val-Cit-SDS-MedChemExpress.pdf
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Protease Cleavable Linker
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
