Didesethyl chloroquine
Didesethyl chloroquine (Bisdesethylchloroquine) is a major metabolite of the antimalarial agent Chloroquine. Didesethyl chloroquine is a potent myocardial depressant[1][2].
Product Specifications
CAS Number
4298-14-0
Product Name Alternative
Bisdesethylchloroquine
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/didesethyl-chloroquine.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCN
Molecular Formula
C14H18ClN3
Molecular Weight
263.77
References & Citations
[1]Biot C, et al. Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds. Bioorg Med Chem. 1999 Dec;7 (12) :2843-7.|[2]Essien EE, et al. Effects of chloroquine and didesethylchloroquine on rabbit myocardium and mitochondria. J Pharm Pharmacol. 1986 Jul;38 (7) :543-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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