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MK-3168 (12C)

Product Specifications

UNSPSC Description

MK-3168 (12C) is a FAAH inhibitor with IC50 values of 1.0, 5.5, 1.7 nM for human, rhesus, rat, respectively. MK-3168 shows good brain uptake and FAAH-specific signal. 11C MK-3168 can be used as FAAH PET tracer[1].

Target Antigen

FAAH

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease;Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mk-3168-12c.html

Smiles

ClC1=CN=C(SC2=C(C3=CC=C([C@H]4C[C@@H]4C(N(C)C)=O)C=C3)N=CN2C)C=C1

Molecular Weight

412.94

References & Citations

[1]Liu P, et al. Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase. ACS Med Chem Lett. 2013 Apr 20;4(6):509-13.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-161965/MK-3168-12C-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-161965/

Clinical Information

No Development Reported

CAS Number

1242441-26-4

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