Caffeoyltryptophan
Caffeoyltryptophan is a competitive PTP1B inhibitor, with an IC50 of 16.99 μM. Caffeoyltryptophan can also inhibit α-glucosidase, linoleic acid peroxidation and haemolysis. Caffeoyltryptophan can be used for the research of type 2 diabetes[1].
Product Specifications
CAS Number
109163-69-1
UNSPSC
12352005
Target
Glycosidase; Phosphatase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/caffeoyltryptophan.html
Purity
98.06
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(C=C1/C=C/C(N[C@H](C(O)=O)CC2=CNC3=CC=CC=C23)=O)=C(C=C1)O
Molecular Formula
C20H18N2O5
Molecular Weight
366.37
References & Citations
[1]Ha MT, et, al. PTP1B and α-glucosidase inhibitory activities of the chemical constituents from Hedera rhombea fruits: Kinetic analysis and molecular docking simulation. Phytochemistry. 2022 May:197:113100. |[2]Ohnishi M, et, al. Inhibition in vitro linoleic acid peroxidation and haemolysis by caffeoyltryptophan. Phytochemistry. 1998 Apr;47 (7) :1215-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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