L-6424
L-6424 inhibits T3 binding to α1-T3R and β1-T3R[1].
Product Specifications
CAS Number
147030-50-0
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-6424.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C(I)=C1)O)C2=C(OC3=CC=CC=C23)CCCC
Molecular Formula
C19H17IO3
Molecular Weight
420.24
References & Citations
[1]H C van Beeren, et al. Structure-function relationship of the inhibition of the 3,5,3'-triiodothyronine binding to the alpha1- and beta1-thyroid hormone receptor by amiodarone analogs. Endocrinology. 1996 Jul;137 (7) :2807-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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