TS-2
TS-2 is a fluorescent ligand of c-Myc G4 with anticancer activity. TS-2 inhibits the growth of cancer cells and induces apoptosis of cancer cells by targeting the c-MYC oncogene promoter G4, causing transcriptional repression of the c-Myc oncogene[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; c-Myc; G-quadruplex
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ts-2.html
Concentration
10mM
Purity
98.27
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[N+]1=C(SC=C1)/C=C/C2=CC(C3=C4C=CC=C3)=C(C=C2)N4C5=CC=CC=C5.[I-]
Molecular Formula
C24H19IN2S
Molecular Weight
494.39
References & Citations
[1]Rui Wang, et al. "Development of a fluorescent ligand that specifically binds to the c-MYC G-quadruplex by migrating the benzene group on a carbazole-benzothiazolium scaffold." Bioorganic Chemistry (2024) : 107690.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6360571-01 0.1 mL
UBAC1, CT (UBAC1, GBDR1, KPC2, UBADC1, Ubiquitin-associated domain-containing protein 1, E3 ubiquitin-protein ligase subunit KPC2, Glialblastoma cell differentiation-related protein 1, Kip1 ubiquitination-promoting complex protein 2) (MaxLight 650)
Ask
View Details