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PSB-603

PSB-603 is a potent and highly selective A2B adenosine receptor antagonist exhibiting a Ki value of 0.553 nM and virtually no affinity for the human and rat A1 and A2A and the human A3 receptors up to a concentration of 10 μM[1].

Product Specifications

CAS Number

1092351-10-4

UNSPSC

12352005

Hazard Statement

H315

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/psb-603.html

Purity

99.38

Solubility

DMSO : 32.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(N1CCC)NC2=C(N=C(C3=CC=C(S(=O)(N4CCN(C5=CC=C(Cl)C=C5)CC4)=O)C=C3)N2)C1=O

Molecular Formula

C24H25ClN6O4S

Molecular Weight

529.01

Precautions

H315

References & Citations

2B2B

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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