PSB-603
PSB-603 is a potent and highly selective A2B adenosine receptor antagonist exhibiting a Ki value of 0.553 nM and virtually no affinity for the human and rat A1 and A2A and the human A3 receptors up to a concentration of 10 μM[1].
Product Specifications
CAS Number
[1092351-10-4]
UNSPSC
12352005
Hazard Statement
H315
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/psb-603.html
Purity
99.38
Solubility
DMSO : 32.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1CCC)NC2=C(N=C(C3=CC=C(S(=O)(N4CCN(C5=CC=C(Cl)C=C5)CC4)=O)C=C3)N2)C1=O
Molecular Formula
C24H25ClN6O4S
Molecular Weight
529.01
Precautions
H315
References & Citations
2B2B
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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