Sinulatumolin D
Sinulatumolin D (compound 4) is an anti-inflammatory agent. Sinulatumolin D has significant TNF-α inhibitory activity with an IC50 value of 5.5 μM[1].
Product Specifications
UNSPSC
12352211
Target
TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sinulatumolin-d.html
Solubility
10 mM in DMSO
Smiles
[H][C@]12CCC([C@@]1([H])[C@]3([H])[C@@](CC[C@]23C)([H])[C@H]([C@@H](/C=C/C(C)(C)O)O)C)=C
Molecular Formula
C20H32O2
Molecular Weight
304.47
References & Citations
[1]Cai YS, et al. Uncommon terpenoids with anti-inflammatory activity from the Hainan soft coral Sinularia tumulosa. Bioorg Chem. 2020 Nov;104:104167.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
TNFRSF5/CD40
Curated Selection
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