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S-(+)-GABOB

Product Specifications

UNSPSC Description

S-(+)-GABOB is an endogenous ligand with antiepileptic activity. S-(+)-GABOB is a metabolite of GABA and may function as a neurotransmitter. S-(+)-GABOB behaves as a full agonist when bound to the ρ(1) wild-type receptor. S-(+)-GABOB acts as a competitive antagonist in the ρ(1) T244S mutant receptor[1].

Target Antigen

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-plus-gabob.html

Purity

97.0

Smiles

O=C(C[C@@H](CN)O)O

Molecular Weight

119.12

References & Citations

[1]Differentiating enantioselective actions of GABOB: a possible role for threonine 244 in the binding site of GABA(C) ρ(1) receptors

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W050122/S-plus-GABOB-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W050122/

Clinical Information

No Development Reported

CAS Number

7013-05-0

Available Sizes

Curated Selection

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