S- (+) -GABOB
S- (+) -GABOB is an endogenous ligand with antiepileptic activity. S- (+) -GABOB is a metabolite of GABA and may function as a neurotransmitter. S- (+) -GABOB behaves as a full agonist when bound to the ρ (1) wild-type receptor. S- (+) -GABOB acts as a competitive antagonist in the ρ (1) T244S mutant receptor[1].
Product Specifications
CAS Number
[7013-05-0]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-plus-gabob.html
Purity
97.0
Solubility
H2O : 20 mg/mL
Smiles
O=C(C[C@@H](CN)O)O
Molecular Formula
C4H9NO3
Molecular Weight
119.12
Precautions
H302, H315, H319, H335
References & Citations
[1]Differentiating enantioselective actions of GABOB: a possible role for threonine 244 in the binding site of GABA (C) ρ (1) receptors
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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