Thymine
Product Specifications
UNSPSC Description
Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.
Target Antigen
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/5-Methylpyrimidine-2,4_1H,3H_-dione.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic)
Smiles
O=C1NC(C(C)=CN1)=O
Molecular Weight
126.11
References & Citations
[1]Tuchman M, et al. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res. 1985 Nov;45(11 Pt 1):5553-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W010450/Thymine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W010450/Thymine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
65-71-4
Available Sizes
Curated Selection
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