MRZ 2-514
Product Specifications
UNSPSC Description
MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with Ki of 33 μM.
Target Antigen
iGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/MRZ_2-514.html
Purity
95.03
Solubility
10 mM in DMSO
Smiles
O=C1NNC(C2=C1C=C3C=C(Br)C=CC3=[N+]2[O-])=O
Molecular Weight
308.09
References & Citations
[1]Parsons CG, et al. Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization. Journal of Pharmacology and Experimental Therapeutics (1997), 283(3), 1264-1275
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101620/MRZ-2-514-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101620/MRZ-2-514-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
202808-11-5
Available Sizes
Curated Selection
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