MRZ 2-514
MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with Ki of 33 μM.
Product Specifications
CAS Number
[202808-11-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/MRZ_2-514.html
Purity
95.08
Solubility
10 mM in DMSO
Smiles
O=C1NNC(C2=C1C=C3C=C(Br)C=CC3=[N+]2[O-])=O
Molecular Formula
C11H6BrN3O3
Molecular Weight
308.09
Precautions
H302, H315, H319
References & Citations
[1]Parsons CG, et al. Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization. Journal of Pharmacology and Experimental Therapeutics (1997), 283 (3), 1264-1275
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Curated Selection
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