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LPPRC rabbit pAb

This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq, Mar 2012],

Product Specifications

Background

This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR) . The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq, Mar 2012]

Gene ID

10128

UniProt

P42704

Cellular Locus

Mitochondrion. Nucleus, nucleoplasm. Nucleus inner membrane. Nucleus outer membrane. Seems to be predominantly mitochondrial.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human LPPRC AA range: 1329-1379

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA, IHC

Validated Applications

WB,ELISA,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES15126-1.pdf

Subcellular Location

Mitochondrion. Nucleus, nucleoplasm. Nucleus inner membrane. Nucleus outer membrane. Seems to be predominantly mitochondrial.

Gene ID (Human)

10128

SwissProt (Human)

P42704

Available Sizes

Curated Selection

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