Human CCR5 Protein, Flag, His Tag (Detergent)
Human CCR5, Flag, His Tag (CC5-H52D1) is expressed from human 293 cells (HEK293) . It contains AA Asp 2 - Arg 223 & Glu 227 - Arg 319 (Accession # P51681-1 (C58Y, G163N, A233D, K303E) ) .
Product Specifications
Background
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.
Specifications
This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.0 kDa. The protein migrates as 40-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .
Accession Number
P51681-1 (C58Y, G163N, A233D, K303E)
Expression Region
Asp 2 - Arg 223 & Glu 227 - Arg 319
Host
HEK293
Target
CCR5
Conjugation
Unconjugated
Tag
N-Flag & C-10xHis
Source
Human
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
85%
Bioactivity
Immobilized Human CCR5, Flag,His Tag (Cat. No. CC5-H52D1) at 10 μg/mL (100 μL/well) can bind Anti-Human CCR5 Antibody with a linear range of 0.02-1.25 μg/mL (QC tested).
Format
Liquid
Buffer
50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Additives
Glycerol
Molecular Weight
46.0 kDa
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
500ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CC5-H52D1.pdf
Species
Human
Curated Selection
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