SARS-CoV-2-IN-86
SARS-CoV-2-IN-86 (Compound 2734589) is SARS-CoV-2 methyltransferases nsp14 and nsp16 inhibitor, Andrographolide (HY-N0191) derivative. SARS-CoV-2-IN-86 has low toxicity, and according to toxicity analysis, the predicted LD50 is 700 mg/kg[1].
Product Specifications
CAS Number
[368866-07-3]
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Drug Derivative; SARS-CoV
Type
Peptides
Related Pathways
Anti-infection; Others
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-in-86.html
Purity
99.90
Solubility
DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
CC(OC(NC1(CCN(CC1)C(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)C(O)=O)=O)(C)C
Molecular Formula
C26H30N2O6
Molecular Weight
466.53
Precautions
H302, H315, H319, H335
References & Citations
[1]Thomas J, et al., Cheminformatics approach to identify andrographolide derivatives as dual inhibitors of methyltransferases (nsp14 and nsp16) of SARS-CoV-2. Sci Rep. 2024 Apr 29;14 (1) :9801.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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