Boc-aminooxy-PEG2-propargyl

Boc-aminooxy-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-aminooxy-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1895922-74-3]

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-nh-peg2-propargyl.html

Purity

97.0

Solubility

10 mM in DMSO

Smiles

C#CCOCCOCCONC(OC(C)(C)C)=O

Molecular Formula

C12H21NO5

Molecular Weight

259.30

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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