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α-Glucosidase-IN-49

α-Glucosidase-IN-49 (compound C23) is a potent inhibitor of α-Glucosidase, with IC50 of 0.52 μM. α-Glucosidase-IN-49 has oral bioactivity that can reduce blood glucose and improve glucose tolerance in mice[1].

Product Specifications

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-49.html

Solubility

10 mM in DMSO

Smiles

O=C(/C(S1)=C/C2=CC=C(C(NC3=NN=C(SCC4=CC=C(C(F)(F)F)C=C4)S3)=O)C=C2)NC1=O

Molecular Formula

C21H13F3N4O3S3

Molecular Weight

522.54

References & Citations

[1]Mengyue Li, et al. Thiazolidine-2,4-dione derivatives as potential α-glucosidase inhibitors: Synthesis, inhibitory activity, binding interaction and hypoglycemic activity. Bioorg Chem. 2024 Mar:144:107177.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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