α-Glucosidase-IN-49
α-Glucosidase-IN-49 (compound C23) is a potent inhibitor of α-Glucosidase, with IC50 of 0.52 μM. α-Glucosidase-IN-49 has oral bioactivity that can reduce blood glucose and improve glucose tolerance in mice[1].
Product Specifications
UNSPSC
12352005
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-glucosidase-in-49.html
Solubility
10 mM in DMSO
Smiles
O=C(/C(S1)=C/C2=CC=C(C(NC3=NN=C(SCC4=CC=C(C(F)(F)F)C=C4)S3)=O)C=C2)NC1=O
Molecular Formula
C21H13F3N4O3S3
Molecular Weight
522.54
References & Citations
[1]Mengyue Li, et al. Thiazolidine-2,4-dione derivatives as potential α-glucosidase inhibitors: Synthesis, inhibitory activity, binding interaction and hypoglycemic activity. Bioorg Chem. 2024 Mar:144:107177.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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