Hepln-13

Hepln-13 is a potent and orally active Hepsin inhibitor with an IC50 of 0.33 μM. Hepln-13 can be used for the research of metastatic prostate cancer[1].

Product Specifications

CAS Number

[64369-13-7]

Product Name Alternative

Clodantoin,Xenazoic acid; CV58913

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Ser/Thr Protease

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hepln-13.html

Purity

99.34

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

BrC1=CC=C(C=C1)C(N2)NC3=C4C2=CC=CC4=CC=C3

Molecular Formula

C17H13BrN2

Molecular Weight

325.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Tang X, et al. Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis. Oncotarget. 2014;5 (5) :1352-1362.