DAU 5884 (hydrochloride)

DAU 5884 hydrochloride is a potent muscarinic M3 receptor antagonist. DAU 5884 hydrochloride inhibits methacholine-dependent effects on cell proliferation and muscle contractility[1].

Product Specifications

CAS Number

[131780-48-8]

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dau-5884-hydrochloride.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

CN([C@@H](CC1)C2)[C@H]1C[C@@H]2OC(N3CC4=CC=CC=C4NC3=O)=O.Cl

Molecular Formula

C17H22ClN3O3

Molecular Weight

351.83

References & Citations

[1]Gosens R, et, al. Muscarinic M3-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle. Am J Respir Cell Mol Biol. 2003 Feb;28 (2) :257-62.