Villalstonine

Product Specifications

CAS Number

[2723-56-0]

UNSPSC Description

Villalstonine is a bisindole alkaloid with various biological activities including anticancer, antimalarial, and antiamoebic activities. Villalstonine exhibits potent antiplasmodial activity against the multidrug-resistant K1 strain of P. falciparum with an IC50 value of 0.27 μM[1].

Target Antigen

Parasite

Type

Natural Products

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/villalstonine.html

Smiles

C/C=C1CN2CCC[C@]3(C[C@]4([H])[C@](C)(O5)OC[C@@]6([H])[C@@]([H])(N7C)CC(C8=C(N9C)C=CC=C8)=C9[C@]7([H])C[C@]64[H])C%10=CC=CC=C%10N([C@@H]%11C(OC)=O)[C@]35[C@]2([H])C[C@@]/1%11[H]

Molecular Weight

674.87

References & Citations

[1]Kamal P Pandey, et al. Bisindole Alkaloids from the Alstonia Species: Recent Isolation, Bioactivity, Biosynthesis, and Synthesis. Molecules. 2021 Jun 7;26(11):3459.