PEG 3350 (Biochemistry Grade)

<strong>PEG 3350</strong>_x000D_ <strong>Catalog number:</strong> B2010063_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 50 g_x000D_ <strong>pH:</strong> na_x000D_ <strong>Supplied as:</strong> Ready-to-use_x000D_ <strong>Appearance:</strong> White Powder_x000D_ <strong>Applications:</strong> hydrophylic polymer with a 3350 MW average. PEG 3350 has been used as crowding agent in immunoturbidimetric assays as well as component of crystallization buffers._x000D_ <strong>Storage:</strong> Room temperature_x000D_ <strong>Keywords:</strong> Polyethylene Glycol, Macrogol_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered on a 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Williams KC, Rogers LK, Hill I, Barnard J, Di Lorenzo C. PEG 3350_x000D_ Administration Is Not Associated with Sustained Elevation of Glycol Levels. J_x000D_ Pediatr. 2018 Apr;195:148-153.e1._x000D_ _x000D_ 2: Jarzebicka D, Sieczkowska-Golub J, Kierkus J, Czubkowski P, Kowalczuk-Kryston_x000D_ M, Pelc M, Lebensztejn D, Korczowski B, Socha P, Oracz G. PEG 3350 Versus_x000D_ Lactulose for Treatment of Functional Constipation in Children: Randomized_x000D_ Study. J Pediatr Gastroenterol Nutr. 2019 Mar;68(3):318-324._x000D_ _x000D_ 3: Brenner DM, Hu Y, Datto C, Creanga D, Camilleri M. A Randomized, Multicenter,_x000D_ Prospective, Crossover, Open-Label Study of Factors Associated With Patient_x000D_ Preferences for Naloxegol or PEG 3350 for Opioid-Induced Constipation. Am J_x000D_ Gastroenterol. 2019 Jun;114(6):954-963._x000D_ _x000D_ 4: Rahimi RS, Singal AG, Cuthbert JA, Rockey DC. Lactulose vs polyethylene_x000D_ glycol 3350--electrolyte solution for treatment of overt hepatic encephalopathy:_x000D_ the HELP randomized clinical trial. JAMA Intern Med. 2014 Nov;174(11):1727-33._x000D_ _x000D_ 5: Tutar E, Bayrak NA, Volkan B, Ertem D. Bowel Preparation for Colonoscopy in_x000D_ Children: 1 Day PEG-3350 with Bisacodyl versus 3 Day Sennosides. Dig Dis._x000D_ 2019;37(4):334-342._x000D_ _x000D_ 6: Khan MA, Patel KB, Nooruddin M, Swanson G, Fogg L, Keshavarzian A, Brown M._x000D_ Polyethylene Glycol-3350 (Miralax®)+1.9-L sports drink (Gatorade®)+2 tablets of_x000D_ bisacodyl results in inferior bowel preparation for colonoscopy compared with_x000D_ Polyethylene Glycol-Ascorbic Acid (MoviPrep®). Turk J Gastroenterol. 2018_x000D_ Jan;29(1):67-74._x000D_ _x000D_ 7: Stone CA Jr, Liu Y, Relling MV, Krantz MS, Pratt AL, Abreo A, Hemler JA,_x000D_ Phillips EJ. Immediate Hypersensitivity to Polyethylene Glycols and_x000D_ Polysorbates: More Common Than We Have Recognized. J Allergy Clin Immunol Pract._x000D_ 2019 May-Jun;7(5):1533-1540.e8._x000D_ _x000D_ 8: Chapman RW, Stanghellini V, Geraint M, Halphen M. Randomized clinical trial:_x000D_ macrogol/PEG 3350 plus electrolytes for treatment of patients with constipation_x000D_ associated with irritable bowel syndrome. Am J Gastroenterol. 2013_x000D_ Sep;108(9):1508-15._x000D_ _x000D_ 9: Cinca R, Chera D, Gruss HJ, Halphen M. Randomised clinical trial:_x000D_ macrogol/PEG 3,350+electrolytes versus prucalopride in the treatment of chronic_x000D_ constipation -- a comparison in a controlled environment.<a href="https://pubmed.ncbi.nlm.nih.gov/23480216/"> Aliment Pharmacol</a>_x000D_ Ther. 2013 May;37(9):876-86._x000D_ _x000D_ <strong>Products Related to PEG 3350 </strong> <a>: Biochemical Buffers and Solutions</a>