Human Cd160 Antigen, CD160 ELISA Kit

CD16 antigen, also known as Natural killer cell receptor BY55 and CD16, is a cell membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD16 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56 (dim) CD16 (+) peripheral blood NK subset. CD16 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD16 is expressed in spleen, peripheral blood, and small intestine. Expression of CD16 is restricted to functional NK and T cytotoxic lymphocytes. CD16 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD16+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD16+ lymphocyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymphocytes release a soluble form of CD16 that functionally impairs the MHC-I-specific cytotoxic CD8 (+) T lymphocyte responsiveness. Cancer Immunotherapy Co-inhibitory Immune Checkpoint Targets Immune Checkpoint Immune Checkpoint Detection: Antibodies Immune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: FCM Antibodies Immune Checkpoint Detection: IHC Antibodies Immune Checkpoint Targets Immunotherapy Targeted Therapy

Concentration | O.D. | Average | Corrected ------------------------------------------ 6000 pg/ml | 2.656 | 2.637 | 2.514 2.617 3000 pg/ml | 1.482 | 1.43 | 1.307 1.378 1500 pg/ml | 0.764 | 0.768 | 0.645 0.772 750 pg/ml | 0.426 | 0.425 | 0.302 0.423 375 pg/ml | 0.278 | 0.272 | 0.149 0.266 187.5 pg/ml | 0.189 | 0.182 | 0.059 0.174 93.75 pg/ml | 0.138 | 0.147 | 0.024 0.155 0 pg/ml | 0.123 | 0.123 | 0 0.122

Intra/Inter-Assay | Sample | n | Mean | Standard Deviation | CV% ---------------------------------------------------------------- Intra-assay | 1 | 20 | 300 | 17.4 | 5.8 Intra-assay | 2 | 20 | 1304 | 53.6 | 4.1 Intra-assay | 3 | 20 | 3835 | 292 | 7.6 Inter-assay | 1 | 20 | 296 | 25.1 | 8.5 Inter-assay | 2 | 20 | 1316 | 114 | 8.6 Inter-assay | 3 | 20 | 3841 | 374 | 9.7

Components | Quantity --------------------- Pre-coated ELISA Plate | 12 x 8 well strips x 1 Standard Solution | 0.2mL x 1 vail Dilution Buffer | 20mL x 1 vail Stop Solution | 6mL x 1 vail Substrate Solution A | 12mL x 1 vail Substrate Solution B | 12mL x 1 vail Wash Buffer Concentrate (25x) | 20mL x 1 vail Detection Antibody Concentrate | 0.6mL x 1 vail