Human Vascular Endothelial Growth Factor Receptor 3, FLT4 ELISA Kit

Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of Signal transduction . The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy

Concentration | O.D. | Average | Corrected ------------------------------------------ 5000 pg/ml | 1.451 | 1.462 | 1.331 1.473 2500 pg/ml | 0.875 | 0.879 | 0.748 0.883 1250 pg/ml | 0.497 | 0.499 | 0.368 0.501 625 pg/ml | 0.312 | 0.319 | 0.188 0.326 312.5 pg/ml | 0.2 | 0.204 | 0.073 0.208 156.25 pg/ml | 0.164 | 0.169 | 0.038 0.174 0 pg/ml | 0.134 | 0.131 | 0 0.128

Intra/Inter-Assay | Sample | n | Mean | Standard Deviation | CV% ---------------------------------------------------------------- Intra-assay | 1 | 20 | 502 | 23.6 | 4.7 Intra-assay | 2 | 20 | 1091 | 47.8 | 4.4 Intra-assay | 3 | 20 | 3410 | 92.1 | 2.7 Inter-assay | 1 | 20 | 504 | 52.6 | 10.4 Inter-assay | 2 | 20 | 1096 | 84.1 | 7.7 Inter-assay | 3 | 20 | 3397 | 229 | 6.7

Components | Quantity --------------------- Pre-coated ELISA Plate | 12 x 8 well strips x 1 Standard Solution | 0.2mL x 1 vail Dilution Buffer | 20mL x 1 vail Stop Solution | 6mL x 1 vail Substrate Solution A | 12mL x 1 vail Substrate Solution B | 12mL x 1 vail Wash Buffer Concentrate (25x) | 20mL x 1 vail Detection Antibody Concentrate | 0.6mL x 1 vail