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Human Hepatitis A Virus Cellular Receptor 1, HAVCR1 ELISA Kit

Product Specifications

Background

HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest levels in the kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy, and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.

Product Name Alternative

Hepatitis A virus cellular receptor 1

Synonyms

KIM1; TIM1; TIMD1; CD365; HAVCR; HAVCR 1

Gene Name

HAVCR1

Gene ID

26762

UniProt

Q96D42

Target

TIM-1

Field of Research

Immunology, Microbiology

Assay Type

Sandwich

Assay Protocol

Concentration | O.D. | Average | Corrected ------------------------------------------ 2800 pg/ml | 2.17 | 2.196 | 2.11 2.221 1400 pg/ml | 1.186 | 1.205 | 1.119 1.223 700 pg/ml | 0.628 | 0.661 | 0.575 0.694 350 pg/ml | 0.398 | 0.378 | 0.292 0.357 175 pg/ml | 0.249 | 0.235 | 0.149 0.221 87.5 pg/ml | 0.154 | 0.162 | 0.076 0.169 43.75 pg/ml | 0.124 | 0.122 | 0.036 0.119 0 pg/ml | 0.088 | 0.086 | 0 0.084

Assay Performance Time

3.5h

Sample Type

Serum, plasma, cell culture supernates

Detection Range

43.75-2800 pg/mL

Precision

Intra/Inter-Assay | Sample | n | Mean | Standard Deviation | CV% ---------------------------------------------------------------- Intra-assay | 1 | 20 | 285 | 12.3 | 4.3 Intra-assay | 2 | 20 | 696 | 22.8 | 3.3 Intra-assay | 3 | 20 | 2110 | 103 | 4.9 Inter-assay | 1 | 20 | 287 | 28.8 | 10 Inter-assay | 2 | 20 | 704 | 48.2 | 6.8 Inter-assay | 3 | 20 | 2103 | 60.9 | 2.9

Sensitivity

13.63 pg/mL

Components

Components | Quantity --------------------- Pre-coated ELISA Plate | 12 x 8 well strips x 1 Standard Solution | 0.2mL x 1 vail Dilution Buffer | 20mL x 1 vail Stop Solution | 6mL x 1 vail Substrate Solution A | 12mL x 1 vail Substrate Solution B | 12mL x 1 vail Wash Buffer Concentrate (25x) | 20mL x 1 vail Detection Antibody Concentrate | 0.6mL x 1 vail

Storage Temperature

2-8°C

Species

Human

Mass

39250

Available Sizes

Frequently Asked Questions

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