Human Erythropoietin Receptor, EPOR ELISA Kit

Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â... single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.

Concentration | O.D. | Average | Corrected ------------------------------------------ 125 pg/ml | 2.634 | 2.528 | 2.433 2.422 62.5 pg/ml | 1.377 | 1.367 | 1.272 1.356 31.25 pg/ml | 0.755 | 0.759 | 0.664 0.763 15.625 pg/ml | 0.44 | 0.427 | 0.332 0.414 7.8125 pg/ml | 0.246 | 0.25 | 0.155 0.254 3.90625 pg/ml | 0.185 | 0.174 | 0.079 0.162 1.953125 pg/ml | 0.139 | 0.134 | 0.039 0.129 0 pg/ml | 0.093 | 0.095 | 0 0.096

Intra/Inter-Assay | Sample | n | Mean | Standard Deviation | CV% ---------------------------------------------------------------- Intra-assay | 1 | 20 | 8.7 | 0.5 | 5.8 Intra-assay | 2 | 20 | 32.4 | 1.3 | 4.1 Intra-assay | 3 | 20 | 72 | 5.6 | 7.7 Inter-assay | 1 | 20 | 8.7 | 0.73 | 8.4 Inter-assay | 2 | 20 | 32.1 | 2.8 | 8.6 Inter-assay | 3 | 20 | 71.6 | 7 | 9.7

Components | Quantity --------------------- Pre-coated ELISA Plate | 12 x 8 well strips x 1 Standard Solution | 0.2mL x 1 vail Dilution Buffer | 20mL x 1 vail Stop Solution | 6mL x 1 vail Substrate Solution A | 12mL x 1 vail Substrate Solution B | 12mL x 1 vail Wash Buffer Concentrate (25x) | 20mL x 1 vail Detection Antibody Concentrate | 0.6mL x 1 vail