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Icenticaftor (QBW251)

Product Specifications

CAS Number

1334546-77-8

Synonyms

NVP-QBW251

Target

CFTR

Applications

Transmembrane Transporters

Molecular Formula

C12H13F6N3O3

Additionnal Information

Icenticaftor (QBW251, NVP-QBW251) is an oral potentiator of the cystic fibrosis transmembrane conductance regulator (CFTR) channel with EC50 of 79 nM and 497 nM for F508del CFTR and G551D CFTR in Fisher Rat Thyroid (FRT) cells.

Storage Conditions

3 years -20°C powder

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