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Zotizalkib

Product Specifications

CAS Number

2648641-36-3

Synonyms

TPX-0131

Target

ALK

Applications

Protein Tyrosine Kinase

Molecular Formula

C21H20F3N5O3

Additionnal Information

Zotizalkib (TPX-0131) is a compact macrocyclic potent CNS-penetrant, next-generation inhibitor of wild-type ALK and ALK-resistant mutations with an IC50 of 1.4 nM for wild-type ALK. It exhibits antitumor efficacy and can be used in non–small cell lung cancer research.

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