G140
Product Specifications
CAS Number
2369751-07-3
Target
CGAS
Applications
Autophagy
Smiles
C[N]1C=CC (=N1) C2=C3C4=C (CCN (C4) C (=O) CO) [NH]C3=C (Cl) C (=C2) Cl
Molecular Formula
C17H16Cl2N4O2
Additionnal Information
G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively.
Storage Conditions
3 years -20°C powder
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