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G140

Product Specifications

CAS Number

2369751-07-3

Target

CGAS

Applications

Autophagy

Smiles

C[N]1C=CC (=N1) C2=C3C4=C (CCN (C4) C (=O) CO) [NH]C3=C (Cl) C (=C2) Cl

Molecular Formula

C17H16Cl2N4O2

Additionnal Information

G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively.

Storage Conditions

3 years -20°C powder

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