CU-CPD107
Product Specifications
CAS Number
2573912-32-8
Target
TLR
Applications
Immunology & Inflammation
Smiles
CCOCC1=NC (=C ([N]1CC (C) (C) O) C2=CC=CC=C2) I
Molecular Formula
C16H21IN2O2
Additionnal Information
CU-CPD107 is a selective, dual-activity small-molecule which demonstrated differential activity against the TLR8 agonists and ssRNA ligands. In the presence of R848, CU-CPD107 acts as a TLR8 signaling inhibitor (IC50=13.7 μM) . In the presence of ssRNA, CU-CPD107 shows synergistic agonist activities, while CU-CPD107 alone is unable to influence TLR8 signaling.
Storage Conditions
3 years -20°C powder
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