ML-SA1

Product Specifications

CAS Number

332382-54-4

Synonyms

Mucolipin synthetic agonist 1

Target

TRP Channel

Applications

Neuronal Signaling

Smiles

CC1CC (C) (C) N (C (=O) CN2C (=O) C3=C (C=CC=C3) C2=O) C4=C1C=CC=C4

Molecular Formula

C22H22N2O3

Additionnal Information

ML-SA1 (Mucolipin synthetic agonist 1) is an activator of TRPML channels. ML-SA1 also inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 values of ML-SA1 against DENV2 RNA and ZIKV RNA are 8.93 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral.