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Vafidemstat

Product Specifications

CAS Number

1357362-02-7

Synonyms

ORY-2001

Target

LSD1

Applications

Epigenetics

Molecular Formula

C19H20N4O2

Additionnal Information

Vafidemstat (ORY-2001) is a potent, selective, brain-penetrant dual inhibitor of lysine-specific histone demethylase (LSD1, KDM1A) and MAO-B, with IC50 values of 105 nM and 58 nM, respectively. It shows potential for treating memory deficits and behavioral alterations in neurodegenerative and psychiatric diseases.

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