Pirtobrutinib (LOXO-305)
Product Specifications
CAS Number
2101700-15-4
Synonyms
LY 3527727, RXC-005
Target
BTK
Applications
Protein Tyrosine Kinase
Smiles
COC1=CC=C (F) C=C1C (=O) NCC2=CC=C (C=C2) C3=N[N] (C (C) C (F) (F) F) C (=C3C (N) =O) N
Molecular Formula
C22H21F4N5O3
Additionnal Information
Pirtobrutinib (LOXO-305, LY 3527727, RXC-005) is a highly selective, non-covalent, next generation BTK inhibitor with an IC50 of 5.69 nM in WT BTK HEK cells. Pirtobrutinib shows more than 300-fold selective for BTK over 98% of 370 other kinases.
Storage Conditions
3 years -20°C powder
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