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IXA4

Product Specifications

CAS Number

1185329-96-7

Target

IRE1

Applications

ER stress & UPR

Smiles

CN (CCOC1=CC=C (C) C=C1) C (=O) C[N]2C=C (NC (=O) CCOC3=CC=CC=C3) C=N2

Molecular Formula

C24H28N4O4

Additionnal Information

IXA4, a highly selective, non-toxic IRE1/XBP1s activator, activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways, and reduces secretion of amyloid precursor protein (APP) through IRE1 activation, preventing APP-associated mitochondrial dysfunction.

Storage Conditions

3 years -20°C powder

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