JHU37160
Product Specifications
CAS Number
2369979-68-8
Target
AChR
Applications
Neuronal Signaling
Smiles
CCN1CCN (CC1) C2=NC3=CC (=CC=C3NC4=C2C=CC=C4F) Cl
Molecular Formula
C19H20ClFN4
Additionnal Information
JHU37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
Storage Conditions
3 years -20°C powder
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