Fatostatin
Product Specifications
CAS Number
125256-00-0
Synonyms
125B11
Target
SREBP
Applications
Metabolism
Smiles
CCCC1=CC (=CC=N1) C2=NC (=CS2) C3=CC=C (C) C=C3
Molecular Formula
C18H18N2S
Additionnal Information
Fatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells.
Storage Conditions
3 years -20°C powder
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SON (SON DNA binding protein, BASS1, C21orf50, DBP-5, FLJ21099, FLJ33914, KIAA1019, NREBP, Bax antagonist selected in Saccharomyces 1, NRE-binding protein, OTTHUMP00000197908, OTTHUMP00000198934, Negative regulatory element-binding protein)
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